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Neuroleptic Malignant Syndrome
Medical Questions » Neuroleptic Malignant Syndrome
| Name: Neuroleptic Malignant Syndrome |
| Also known as: |
| Very rare (under 200 cases reported) complication of medication used for severe psychiatric disturbances. |
Causes of Neuroleptic Malignant Syndrome
May occur early or late in use of major tranquillizers (eg. phenothiazines, butyrophones, thioxanthines, loxapine) at normal dosages. |
Symptoms of Neuroleptic Malignant Syndrome
Very high fever, muscular rigidity, tremor, abnormal sweating, confusion and loss of consciousness. |
Tests for Neuroleptic Malignant Syndrome
Some blood tests may be abnormal, but none specifically diagnostic. |
Treatment for Neuroleptic Malignant Syndrome
Cease medication and support in hospital intensive care unit. Numerous medications have been trialed to help patients, but none proven effective.
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Complications of Neuroleptic Malignant Syndrome of its treatment
Rhabdomyolysis (muscle meltdown). |
Likely Outcome of Neuroleptic Malignant Syndrome
Death in 20%. Early treatment improves mortality. |
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