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Pemphigus

Medical Questions » Pemphigus
Name: Pemphigus
Also known as:
A rare but severe skin disease that occurs in all age groups and both sexes, but is very uncommon in children.
Causes of Pemphigus
Auto-immune disease in which there is an inappropriate immune reaction within the body that causes the skin to be rejected in the same way as a transplanted kidney is rejected by the body. The actual cause of the autoimmune reaction is unknown.
Symptoms of Pemphigus
Rash varies dramatically in its form from shallow ulcers, to multiple blisters, red scaling patches or massive peeling of skin. Any part of the body, including the face and the inside of the mouth, may be affected.
Tests for Pemphigus
A biopsy (sample) of the affected skin is examined to confirm the diagnosis.
Treatment for Pemphigus
Large doses of prednisone or other steroids, immunosuppressive and cytotoxic drugs, all of which may have significant side effects, must be used long-term.
Complications of Pemphigus of its treatment
None significant.
Likely Outcome of Pemphigus
Without treatment, pemphigus is invariably fatal. With adequate treatment, the mortality rate is below 25%.
       
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