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Urticaria Pigmentosa
Medical Questions » Urticaria Pigmentosa
| Name: Urticaria Pigmentosa |
| Also known as: Mastocytosis |
| Allergy-like patch reaction in skin that most often affects infants. |
Causes of Urticaria Pigmentosa
Patches are made of abnormal collections of mast cells. These contain histamine and when the cell is disturbed, this is released into the skin. Histamine makes blood vessels leak, resulting in localized itching, swelling
and redness. |
Symptoms of Urticaria Pigmentosa
Brown patches on the skin of young children that steadily increase in number over several months or years and blister when rubbed. If many patches are activated at the same time the skin becomes itchy and the infant may become irritable, but it is uncommon for severe symptoms to arise. |
Tests for Urticaria Pigmentosa
Rubbing a patch causes redness, swelling and itching within a few minutes (Darier' s sign). Occasionally a skin biopsy is needed to confirm the diagnosis. |
Treatment for Urticaria Pigmentosa
None normally necessary. Exercise, heat, alcohol and some medications (eg. aspirin, narcotics codeine and morphine) can aggravate the condition. If symptoms are significant antihistamine mixture or tablets, and steroid creams can be used.
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Complications of Urticaria Pigmentosa of its treatment
A severe attack can result in flushing and faintness. Rarely occurs in adults, when the condition is usually worse, spots are itchier, and may spread to involve internal organs (systemic mastocytosis). |
Likely Outcome of Urticaria Pigmentosa
Over the next few years becomes less irritable and eventually the patches fade away. By the teenage years, most patches will have gone. |
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