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Wilms' Tumour

Medical Questions » Wilms' Tumour
Name: Wilms' Tumour
Also known as: Nephroblastoma
A form of cancer that arises in the supportive tissue immediately surrounding the kidneys of children.
Causes of Wilms' Tumour
Unknown. More than 80% of patients are under four years of age when diagnosed, and it accounts for nearly 10% of all childhood cancers.
Symptoms of Wilms' Tumour
The children develop a swollen abdomen, but only one in five has pain, and even fewer develop the other possible symptoms of fever, bloody urine, weight loss and loss of appetite. Usually detected by a parent feeling the large hard mass in the abdomen.
Tests for Wilms' Tumour
Diagnosis confirmed by X-ray or CT scan of the kidney, followed by a biopsy.
Treatment for Wilms' Tumour
The affected kidney is removed surgically, followed by irradiation of the abdomen to destroy any remaining cancer cells. Chemotherapy with cytotoxic drugs may also be given.
Complications of Wilms' Tumour of its treatment
Spread of the cancer to other tissues and organs, particularly the liver and lungs, and in rare cases to the bone and brain.
Likely Outcome of Wilms' Tumour
With localized disease 90% of patients now survive more than five years, and even if the cancer has spread to other organs, more than 50% survive for five years.
       
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