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Zollinger-Ellison Syndrome

Medical Questions » Zollinger-Ellison Syndrome
Name: Zollinger-Ellison Syndrome
Also known as: Gastrinoma
Rare form of severe peptic ulceration in the stomach or small intestine.
Causes of Zollinger-Ellison Syndrome
A tumor of the pancreas that produces high levels of a hormone which promotes excessive acid production in the stomach.
Symptoms of Zollinger-Ellison Syndrome
Exaggerated symptoms of a peptic ulcer with severe pain in the upper abdomen, bloating, nausea and diarrhoea. Usually starts at a younger age than normal for a peptic ulcer.
Tests for Zollinger-Ellison Syndrome
A specific blood test can measure the hormone ' gastrin' which is responsible for stimulating the stomach to produce hydrochloric acid. Other tests include gastroscopy and measuring the amount of acid in the stomach.
Treatment for Zollinger-Ellison Syndrome
Medications as for normal peptic ulcers, but in higher doses. Surgery is often required to control recurrent ulceration.
Complications of Zollinger-Ellison Syndrome of its treatment
Severe bleeding from ulcers leading to anemia.
Likely Outcome of Zollinger-Ellison Syndrome
Treatment must be continued lifelong, but is usually successful in controlling the disease.
       
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